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radio lab: mortality.

i was listening to KUT and there was an awesome segment called "radio lab" and today's segment was on aging.

It was extremely fascinating. I've heard about the counter in cells that keeps track and limit reproduction, but never had it explained in such a lucid way. The counter is like a train track, a bunch of buffers, that each time you reproduce, a segment is removed, until you reach the 50th or so, which is a sensor telling the cells to stop reproduction. An enzyme, tellurase, allows the segment to be reattached once it is removed. However, it's also an enzyme that is found in most tumor/cancer cells.

Then they moved on to an awesome woman professor in UC Berkeley, who was talking about her round worms with such enthusiam: see how lively and wonderful they look?
She has managed to extend their lives up to 6 times longer, by crippling the "grim reaper" gene, which allows a fountain of life like gym to act uninhibited and activate 100 other genes, as well as modifying some genes related to reproduction, which causes the worms to live long long lives. The whole concept is astounding. Scary and awesome at once.

I forgot how much science excites me.

Comments

( 3 comments — Leave a comment )
orangepaisley
Aug. 17th, 2007 11:42 pm (UTC)
I heart science
OMG, I was listening to this today, too. I love this show. Did you hear the episode on Wednesday about zoos? It was awesome and very touching.
ripresa
Aug. 18th, 2007 04:34 am (UTC)
Re: I heart science
it's the first time i've heard of it. it's pretty awesome.
dnivie
Aug. 22nd, 2007 12:10 pm (UTC)
Telomeres ?
Yeah, it's fascinating. I thougth the role of telomeres in aging had been revised downwards in recent years though ? Hmm, maybe I was just imagining that, I'm seriously out of date in biology.

Science is cool. Some of the mechanisms discovered even in simple organisms are mindboggling. slime-molds are a neat trick, for starters.
( 3 comments — Leave a comment )

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